Melanoma

February 25, 2015February 25, 2015

Decreased RNA-Editing Promotes Melanoma Progression

Melanoma, News

A new study entitled “Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis” showed how lack of RNA-editing, a key cellular process whereby RNA nucleotides are modified, contributes to tumor ... Read more

February 19, 2015February 19, 2015

Screening Strategies and Monitoring Patients at Risk of Melanoma Crucial for Early Detection

Melanoma, News

According to a recent clinical review published in The Journal of the American Medical Association, promoting screening strategies and monitoring patients at extreme risk of melanoma is crucial for early ... Read more

February 18, 2015February 18, 2015

NYU Langone Researchers Find Two Molecules Able to Suppress Melanoma Spread

Melanoma, News

Researchers at NYU Langone Medical Center and NYU Langone’s Laura and Isaac Perlmutter Cancer Center recently reported their findings on two molecules of non-coding genetic material that are able to ... Read more

February 17, 2015February 17, 2015

Intralesional Treatment Identified As Promising Therapy For Advanced Melanoma

Melanoma, News

In a recent review article entitled “Intralesional therapy for advanced melanoma: promise and limitation,” Dr. Sanjiv S. Agarwala from St. Luke’s Cancer Center and Temple University in Pennsylvania discusses the need for several ... Read more

February 11, 2015February 11, 2015

New Target Protein Could Overcome Melanoma Drug Resistance

Melanoma, News

An international research team led by Dr. Trever Bivona of the University of California San Francisco (UCSF) identified a protein responsible for melanoma drug resistance. The study, published online in Nature Genetics, ... Read more

February 10, 2015February 10, 2015

Researchers Receive Grant to Study Melanoma Metastasis

Melanoma, News

Rutgers Cancer Institute of New Jersey and Ernest Mario School of Pharmacy researchers have been granted $200,000 to study the underlying mechanisms of melanoma metastasis. The grant awarded by the National ... Read more

January 15, 2015January 15, 2015

Metastatic Melanoma in Mice Treated with ALS Therapeutic and Radiation

Melanoma, News

Melanoma that has metastasized to the brain may be more effectively treated using radiation therapy in combination with the drug riluzole than with radiation alone. Researchers at Rutgers Cancer Institute ... Read more

January 12, 2015January 12, 2015

Genetic Test for Melanoma Metastasis from Castle Biosciences Validated in Recent Study

Melanoma, News

A recent study published in Clinical Cancer Research, “Development of a Prognostic Genetic Signature to Predict the Metastatic Risk Associated with Cutaneous Melanoma,” used Texas-based Castle Bioscience’s DecisionDx-Melanoma test for cutaneous ... Read more

January 8, 2015January 8, 2015

Melanoma Pigmentation Linked to Mitochondrial ROS Levels

Melanoma, News

A new study from The Medical School of Newcastle University is assigning guilt by association to mitochondrial function and melanoma. Melanoma skin cancer cells that display high levels of pigmentation ... Read more

November 26, 2014November 26, 2014

Study Finds Key Mutations in Melanoma Patients Responsive to Immunotherapy

Melanoma, News

Timothy Chan, MD, PhD, and oncology fellow Alexandra Snyder Charen, MD, at the Memorial Sloan Kettering Cancer Center, are working to advance the way melanoma patients are treated with immunotherapy. The ... Read more

November 12, 2014

Tumor Thickness Indicates 10-Year Survival for Mucosal Melanoma

Melanoma, News

When thinking of melanoma, skin cancer due to ultraviolet radiation usually comes to mind. Less commonly, about 1% of melanoma patients can develop mucosal melanoma, which is associated with a ... Read more

October 29, 2014

Metastasectomies Following Systemic Treatment Discussed in Panel

Melanoma, News

Surgery following systemic therapy against melanoma is a widely discussed topic in the world of clinical oncology. OncLive, a platform of information concerning cancers that include lung, leukemia, and melanoma, ... Read more

October 20, 2014October 20, 2014

Melanoma Patients Often Carry TERT Promoter Mutations

Melanoma, News

A group at University Hospital Essen in German confirmed the commonality of mutations in the gene for telomerase reverse transcriptase (TERT) in patients with cutaneous melanoma through a new study ... Read more

October 15, 2014October 15, 2014

Melanoma Cells Use LPA Gradient to Migrate Around Body

Melanoma, News

As melanoma is one of the fastest spreading, aggressive cancer types, researchers are constantly trying to understand melanoma cells in order to stop their spread in the body. At the ... Read more

October 14, 2014October 14, 2014

Understanding Mutations, micro-RNAs, and Melanoma at Toldeo University

Melanoma, News, Skin Cancer

At University of Toledo, the laboratories of Drs. Kam Yeung and Ivana de la Serna discovered a new explanation for aggressive melanoma. Ila Datar, a PhD graduate student in the ... Read more

September 30, 2014September 30, 2014

Array’s Melanoma Drug Promising in Phase 2 Study

Melanoma, News

Array BioPharma Inc. recently presented the latest results of its Phase 2 clinical trial of binimetinib in patients with advanced NRAS mutant melanoma, at the European Society for Medical Oncology (ESMO) Annual Meeting ... Read more

September 29, 2014September 29, 2014

FDA Grants Priority Review to Nivolumab For Melanoma Treatment

Melanoma, News

PD-1 inhibitor nivolumab (Opdivo) has been granted a priority review designation by the American Food and Drug Association (FDA), as a treatment for pretreated patients with advanced melanoma. This decision ... Read more

September 25, 2014September 25, 2014

Results On New Melanoma Drug PV-10 To Be Presented At The European Society for Medical Oncology Congress

Melanoma, News

During this year’s European Society for Medical Oncology (ESMO) 2014 Congress, drug developer Provectus Biopharmaceuticals, Inc., will present a study entitled, “Subgroup efficacy in patients receiving intralesional rose bengal to all existing ... Read more

September 24, 2014September 24, 2014

Telomeres Length May Influence Risk of Developing Melanoma

Melanoma, News

People who have longer telomeres, a compound structure at the end of a chromosome, have higher risk of suffering from melanoma, according to the study “The effect on melanoma risk of ... Read more

September 23, 2014September 23, 2014

PD-L1 in Melanoma Identified As Negative Prognostic Marker

Melanoma, News

In a new study entitled “PD-L1 marks a subset of melanomas with a shorter overall survival and distinct genetic and morphological characteristics”, published in the Annals of Oncology journal, a ... Read more