News

October 11, 2016October 11, 2016

High Risk Melanoma Patients Given Yervoy After Surgery Improved Overall Survival

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Patients with high risk melanoma who undergo surgery to remove their tumors may markedly benefit from Yervoy (ipilimumab) following surgery, according to the results of a Phase 3 trial. The ... Read more

October 6, 2016

Studies Focus on Side Effects of Combining Melanoma Immunotherapies

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Combining immunotherapy with other cancer treatments in patients with malignant melanoma can improve outcomes, but is associated with increased side effects. Now, researchers at Vienna General Hospital Comprehensive Cancer Center are ... Read more

October 4, 2016October 4, 2016

Ability of Yervoy to Treat Melanoma May Depend on Mutations in Tumor Cells

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Melanoma tumors harboring mutations that inactivate interferon (IFN)-gamma signaling are resistant to treatment with the checkpoint inhibitor Yervoy (ipilimumab), researchers report. The findings may be used to predict which patients may ... Read more

September 29, 2016

Immuno, Radiation Combo Better than Chemo for Melanoma Brain Metastasis Outcomes

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Therapies that target elements of the immune system or certain pathways active in cancer cells, in combination with radiation therapy, may work better than chemotherapy for patients with melanoma brain metastases,  according ... Read more

September 27, 2016

Investigational Combination Therapy Shows Promising Results in Specific Melanoma Patients

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Melanoma patients with BRAF mutations may benefit more from the combination of encorafenib and binimetinib, two investigational medicines, than from Zelboraf (vemurafenib) monotherapy, according to data from the first part ... Read more

September 22, 2016

Using High-Factor Sunscreen Can Markedly Reduce Melanoma Risk

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The use of high-factor sunscreen can decrease the risk of developing melanoma, according to a study published recently in the Journal of Clinical Oncology. The study, “Sunscreen Use and Subsequent Melanoma ... Read more

September 20, 2016

Melanoma ‘Walk and Fun Run’ Raises Money for MD Anderson Research

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The University of Texas MD Anderson Cancer Center and the AIM at Melanoma Foundation joined to host the 9th Annual AIM for the CURE Melanoma Walk and Fun Run to promote ... Read more

September 15, 2016

Rapid Detection of Malignant Melanoma Mutation Now Possible Using Nanotechnology

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A new nanotechnology method can easily and quickly detect genetic changes in tissue samples. The innovative method developed by researchers from the Swiss Nanoscience Institute at the University of Basel ... Read more

September 13, 2016September 13, 2016

Experimental Therapy Shows Notable Promise in Treating Melanoma and Other Cancers

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An experimental cancer drug called pevonedistat appears to be quite promising against melanoma and possibly other forms of cancer, according to a recent study from the University of Virginia (UVA) School of Medicine. In ... Read more

September 8, 2016

Autophagy Protein May Serve as Melanoma Prognosis Biomarker, Researchers Find

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Researchers have discovered a protein that can be used to predict the prognosis and response to treatment of malignant melanoma, a process that is currently done primarily by observing features of the ... Read more

September 6, 2016September 6, 2016

Diagnosing Melanoma Appears More Accurate Using New Test Compared to Traditional Method, Study Finds

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A new study suggests that mass spectrometry imaging, a technique that allows the identification of several molecules, such as metabolites, peptides and proteins, DNA segments, and lipids from tissue samples, ... Read more

September 1, 2016September 1, 2016

Advanced Head and Neck Melanomas Often Found Where They’re Hardest to See

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Advanced-stage cutaneous head and neck melanomas are diagnosed more often on the scalp or back of the neck than toward the front of the body, like the face or ears, according to a ... Read more

August 30, 2016August 30, 2016

New Research Shows How Melanoma Cells Reach Blood Vessels, Reveals Chemicals for Prevention

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To reach circulation and invade other organs, melanoma cells must travel from the epidermis (outer layer of skin) where there is marked absence of blood vessels, to the dermis (deeper level ... Read more

August 25, 2016August 25, 2016

Melanomas Associated with Moles Have Better Prognosis Than Those Without Moles, Study Finds

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Nevus-associated melanomas, or melanomas that are associated with a mole, are less likely to have an adverse histopathology than de novo melanomas, or melanomas that arise from clinically normal skin ... Read more

August 23, 2016August 23, 2016

US Preventive Services Task Force Updates Skin Cancer Screening Recommendation

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A US Preventive Services Task Force has concluded after careful review that current evidence is insufficient to adequately determine the benefit versus harm of having clinicians conduct routine visual skin cancer screenings. The recommendation does ... Read more

August 18, 2016August 18, 2016

Opdivo Seen to Improve Life Quality in People with Advanced Melanoma

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Nivolumab not only improves survival but also maintains or even improves health related quality of life in patients with advanced melanoma, according to a study funded by Bristol-Myers Squibb, its ... Read more

August 16, 2016August 16, 2016

Analyzing Melanoma Tumor Biopsies During Treatment Could Help Predict Patients’ Response to Therapy, Study Reports

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Although analyzing biopsies from melanoma patients before the start of a treatment cannot reliably predict which patients will respond to treatment and which ones will not, measuring immune response in ... Read more

August 11, 2016August 11, 2016

Melanoma: Mechanism Behind BRAF-Mutant Resistance to Therapies Identified

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Massachusetts General Hospital (MGH) researchers have identified a previously unknown mechanism that allows BRAF-mutant melanoma cells to resist targeted therapies. The study “Loss of cohesin complex components STAG2 or STAG3 confers resistance ... Read more

August 9, 2016August 9, 2016

Noncoding RNA Could Be Target for Melanoma Therapy Development

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Inhibition of a long noncoding RNA called RMEL3 may help treat melanoma patients, including those with a BRAF mutation, according to a recent study developed by researchers at the University ... Read more

August 4, 2016August 4, 2016

Keytruda Shows Early Promise in Melanoma Brain Metastases, Study Suggests

News

Pembrolizumab, trade name Kertruda, an antibody used in cancer immunotherapy, may have therapeutic effects in brain metastases in patients with melanoma and non–small cell lung cancer (NSCLC), as suggested by ... Read more