News

March 25, 2015March 25, 2015

UCLA Researchers Develop Effective Triple Combination Therapy for Melanoma

Melanoma, News

Researchers at the University of California, Los Angeles (UCLA) recently published in the journal Science Translational Medicine results of a groundbreaking effective triple combination therapy for advanced melanoma. The study is ... Read more

March 24, 2015March 24, 2015

How Advanced Melanoma Treatments Can Improve Patient Survival

Melanoma, News

When melanoma is detected early, treatment can be highly successful. However, survival rates decrease significantly when cancer cells spread to the lymph nodes and other organs. In the last 5 years, targeted therapy and ... Read more

March 23, 2015March 23, 2015

Melanoma Mortality Expected to Vanish in Light-Skinned Populations by 2050

News

A reduction in the mortality rate of cutaneous malignant melanoma, the most lethal form of skin cancer, is on the horizon for light-skinned populations, a recent study published in the ... Read more

March 20, 2015March 20, 2015

Research Shows Standard Treatments Not Effective Against Nodal in Metastatic Melanoma

Melanoma, News

A recent study published in Molecular Cancer Research, led by researchers from the laboratory of Mary J.C. Hendrix, found that standard treatments to address metastatic melanoma are ineffective against Nodal, a growth factor protein. ... Read more

March 19, 2015March 19, 2015

Novel Immunotherapy Drug Pembrolizumab ‘Fast-Tracked’ for Advanced Melanoma

Melanoma, News

Under a new United Kingdom Government scheme, the novel immunotherapy drug Pembrolizumab has become the first treatment ‘fast-tracked’ for National Health Service (NHS) patients with advanced melanoma. “It’s a step ... Read more

March 18, 2015March 18, 2015

Macrophages – The Missing Link in Melanoma Resistance to BRAF Therapy

News

In a new study entitled “BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth,” researchers suggest that a specific type of immune cell — macrophages — offers a potential new therapeutic ... Read more

March 17, 2015March 17, 2015

Researchers Discover Genetic Alterations in Children and Adolescents with Melanoma

Melanoma, News

Researchers from the St. Jude Children’s Research Hospital — Washington University Pediatric Cancer Genome Project were able to identify the genetic foundations of three different pediatric melanoma subtypes. These new ... Read more

March 16, 2015March 16, 2015

DermSpectra Nikon D810 Camera Integration Provides a High Resolution Skin Imaging Solution

Melanoma, News

DermSpectra — a startup firm specializing in the field of digital medical imaging systems — has announced a new OEM relationship with Japanese photography and optics Nikon Inc. Under terms ... Read more

March 13, 2015March 13, 2015

Delcath Submits Findings of Phase 3 Trial In Top Peer-reviewed Journal

Melanoma, News

Delcath Systems, Inc. a specialty pharmaceutical and device company with a primary focus on developing treatments for primary and metastatic liver cancer recently announced the publication of their Phase 3 ... Read more

March 11, 2015March 12, 2015

TGF-β Signals Can Influence Melanoma Cells’ Vulnerability To Drugs

News

A recent study published in Cell and titled “The Harmonies Played By TGF-β in Stem Cell Biology,” assessed how cancer cells respond to transforming growth factor beta (TGF-β) signals. These discoveries can lead to new approaches ... Read more

March 11, 2015March 11, 2015

Radiation Combined With Immunotherapy May Provide Optimal Response For Metastatic Melanoma

Melanoma, News

A new treatment strategy combining radiation therapy and two immunotherapies that target the CTLA4 and PD-1 pathways was recently shown to induce an optimal response in patients with metastatic melanoma. ... Read more

March 10, 2015April 21, 2015

FTC to Pursue Charges Against Melanoma Detection Apps

Melanoma, News

The Federal Trade Commission (FTC) has opened a case to end fraudulent advertisement regarding mobile apps that are supposed to diagnose melanoma through detecting symptoms or pictures of moles. While two marketers, MelApp ... Read more

March 9, 2015March 9, 2015

FDA Accepts Supplemental Biologics License Application for Yervoy as Adjuvant Treatment for Stage 3 Melanoma Patients

Melanoma, News

Bristol-Myers Squibb recently announced that the U.S. Food and Drug Administration (FDA) accepted the filing and review of the supplemental Biologics License Application (sBLA) for Yervoy (ipilimumab), a medication for the ... Read more

March 6, 2015March 6, 2015

Researchers Discover Pathway Responsible for Taste Loss in Skin Cancer Patients Under Chemotherapy Treatment

News, Skin Cancer

Researchers at the University of Michigan have recently discovered the molecular pathway that explains why patients under chemotherapy treatment experience changes in taste. The study was published in the Journal ... Read more

March 5, 2015March 5, 2015

Oleocanthal in Olive Oil Pokes Holes in Cancer Cells

News, Skin Cancer

Working in a laboratory at Rutgers University, Drs. Paul Breslin, David Foster, and Onica LeGendre discovered how a chemical component of olive oil kills human cancer cells derived from skin ... Read more

March 4, 2015March 4, 2015

Pioneering Blood-Based Biomarker Strategy Allows Early Cancer Detection in Mice

Melanoma, News

Researchers at Stanford University School of Medicine in California have recently revealed a new strategy for cancer detection via the use of blood-based biomarkers. The study is entitled “Detecting cancers ... Read more

March 3, 2015March 3, 2015

CURE OM Encourages Ocular Melanoma Patients to Share Stories

Melanoma, News

The Melanoma Research Foundation‘s Community United for Research and Education of Ocular Melanoma (CURE OM) program recently commended Oliver Sacks, a patient with ocular melanoma (OM), for sharing his experiences with the disease in ... Read more

March 2, 2015March 2, 2015

MD Anderson Studies Melanoma Patients Resistant To Therapy

Melanoma, News

Researchers from The University of Texas MD Anderson Cancer Center may have found a way to accurately predict which patients will be more likely to respond to genomic-based follow-up therapies by interpreting unique ... Read more

February 26, 2015February 26, 2015

Melanoma’s Addiction To Glutamine Explains Cancer Growth

News

Researchers from the Sanford-Burnham Medical Research Institute discovered that without a source of glutamine (one of the amino acids forming proteins) melanoma cells stop proliferating and die. Melanoma cells crave glutamine since they can overuse this essential nutrient as an ... Read more

February 25, 2015February 25, 2015

Decreased RNA-Editing Promotes Melanoma Progression

Melanoma, News

A new study entitled “Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis” showed how lack of RNA-editing, a key cellular process whereby RNA nucleotides are modified, contributes to tumor ... Read more